Chelsea Handler made headlines at the 2025 Critics' Choice Awards, not just for her comedic hosting skills but for a visible medical accessory on her arm: a PICC line. The annual event, broadcast live from Santa Monica, Calif., saw Handler take to the stage with her left arm wrapped in a bandage. While some attendees might have been curious about this unusual accessory, the comedian addressed it head-on during her opening monologue.
What Is a PICC Line?
A PICC line, or peripherally inserted central catheter, is a long, thin tube inserted into a vein in the arm and guided toward larger veins near the heart. It's commonly used to deliver medications, fluids, or nutrition directly into the bloodstream over an extended period. According to the Mayo Clinic, this device is often employed when patients require prolonged treatment, such as antibiotics or chemotherapy.
In her characteristic humor, Handler quipped, “Some of you may be wondering what’s going on here. I have a PICC line in my arm. No, I’m not on The Substance—though Sydney Sweeney might disagree.” Her joke referenced the film The Substance, which was nominated that evening, adding levity to what could otherwise be perceived as a serious health issue.
Why Did Chelsea Handler Need a PICC Line?
While Handler hasn’t explicitly detailed why she required the PICC line, she previously disclosed having undergone surgery to address a shoulder infection. In a podcast appearance with Alex Cooper, she explained that she had received a PRP (platelet-rich plasma) injection to alleviate symptoms until she could undergo further surgical intervention.
Handler also mentioned being prescribed Vicodin for pain management related to the infection. Despite these challenges, she maintained her signature wit throughout the awards show, ensuring the audience remained entertained while subtly addressing concerns about her well-being.
A Night of Comedy and Courage
As one of the most anticipated events in Hollywood's calendar, the Critics' Choice Awards brought together celebrities, filmmakers, and industry insiders to celebrate cinematic excellence. Hosting for the third consecutive year, Chelsea Handler ensured the evening stayed lighthearted despite her own health struggles.
Her decision to openly discuss the PICC line reflects her transparency and willingness to normalize conversations around healthcare and personal wellness. Fans appreciated her honesty, with many taking to social media to express their support. One Twitter user commented, “Whatever the PICC line is for, I hope you’re recovering swiftly!” Another Instagram post read, “Had so much fun last night @criticschoice! Thanks for keeping us laughing through it all.”
Beyond Entertainment: A Focus on Health
For those unfamiliar with PICC lines, Handler’s public acknowledgment provided an opportunity to educate others about their purpose and importance. Medical professionals, including certified child life specialists like Lindsey Reynolds, MS, CCLS, frequently work with patients requiring such devices. These specialists ensure children and adults alike feel comfortable and informed during procedures involving PICC lines, lumbar punctures, or other invasive treatments.
Reynolds, who works at Penn State Health Children’s Hospital, emphasized the need for developmentally appropriate preparation when introducing young patients to medical equipment. By fostering trust and understanding, healthcare providers can minimize anxiety and promote healing.
Conclusion: Balancing Humor and Humanity
Chelsea Handler has always been known for pushing boundaries and challenging societal norms. At the 2025 Critics' Choice Awards, she did just that by turning a potentially sensitive topic into a moment of connection with her audience. Whether discussing skin treatments like ProFractional Lasers or embracing her role as a patient advocate, Handler continues to inspire fans worldwide.
As she joked during her monologue, “It ends with us, guys. Come get me.” For Handler, resilience isn’t just about surviving adversity—it’s about thriving amidst it, one laugh at a time.
